MLB scores, schedule and odds: Tuesday, September 21, 2027
The MLB schedule for Tuesday, September 21, 2027 has 15 games.
First up: Cubs at Phillies at 12:00 AM ET on MLB.TV.
- Chicago Cubs at Philadelphia Phillies — Tue, Sep 21 12:00 AM ET · Citizens Bank Park, Philadelphia
- Cincinnati Reds at Baltimore Orioles — Tue, Sep 21 12:00 AM ET · Oriole Park at Camden Yards, Baltimore
- Detroit Tigers at Chicago White Sox — Tue, Sep 21 12:00 AM ET · Rate Field, Chicago
- Houston Astros at Athletics — Tue, Sep 21 12:00 AM ET · Sutter Health Park, Sacramento
- Kansas City Royals at Cleveland Guardians — Tue, Sep 21 12:00 AM ET · Progressive Field, Cleveland
- Los Angeles Dodgers at Colorado Rockies — Tue, Sep 21 12:00 AM ET · Coors Field, Denver
- Miami Marlins at Texas Rangers — Tue, Sep 21 12:00 AM ET · Globe Life Field, Arlington
- Milwaukee Brewers at St. Louis Cardinals — Tue, Sep 21 12:00 AM ET · Busch Stadium, St. Louis
- New York Yankees at Toronto Blue Jays — Tue, Sep 21 12:00 AM ET · Rogers Centre, Toronto
- Pittsburgh Pirates at New York Mets — Tue, Sep 21 12:00 AM ET · Citi Field, Queens
- San Diego Padres at Arizona Diamondbacks — Tue, Sep 21 12:00 AM ET · Chase Field, Phoenix
- Seattle Mariners at Los Angeles Angels — Tue, Sep 21 12:00 AM ET · Angel Stadium, Anaheim
- San Francisco Giants at Minnesota Twins — Tue, Sep 21 12:00 AM ET · Target Field, Minneapolis
- Tampa Bay Rays at Boston Red Sox — Tue, Sep 21 12:00 AM ET · Fenway Park, Boston
- Washington Nationals at Atlanta Braves — Tue, Sep 21 12:00 AM ET · Truist Park, Atlanta