MLB scores, schedule and odds: Thursday, September 16, 2027

The MLB schedule for Thursday, September 16, 2027 has 14 games.

First up: Angels at Astros at 12:00 AM ET on MLB.TV.

• Los Angeles Angels at Houston Astros — Thu, Sep 16 12:00 AM ET · Daikin Park, Houston
• Arizona Diamondbacks at Los Angeles Dodgers — Thu, Sep 16 12:00 AM ET · Dodger Stadium, Los Angeles
• Athletics at Tampa Bay Rays — Thu, Sep 16 12:00 AM ET · Tropicana Field, St. Petersburg
• Atlanta Braves at San Diego Padres — Thu, Sep 16 12:00 AM ET · Petco Park, San Diego
• Baltimore Orioles at Chicago Cubs — Thu, Sep 16 12:00 AM ET · Wrigley Field, Chicago
• Boston Red Sox at Milwaukee Brewers — Thu, Sep 16 12:00 AM ET · American Family Field, Milwaukee
• Chicago White Sox at New York Yankees — Thu, Sep 16 12:00 AM ET · Yankee Stadium, Bronx
• Cleveland Guardians at Kansas City Royals — Thu, Sep 16 12:00 AM ET · Kauffman Stadium, Kansas City
• Colorado Rockies at Miami Marlins — Thu, Sep 16 12:00 AM ET · loanDepot park, Miami
• Minnesota Twins at Detroit Tigers — Thu, Sep 16 12:00 AM ET · Comerica Park, Detroit
• New York Mets at Washington Nationals — Thu, Sep 16 12:00 AM ET · Nationals Park, Washington
• Philadelphia Phillies at Cincinnati Reds — Thu, Sep 16 12:00 AM ET · Great American Ball Park, Cincinnati
• St. Louis Cardinals at Pittsburgh Pirates — Thu, Sep 16 12:00 AM ET · PNC Park, Pittsburgh
• Texas Rangers at Seattle Mariners — Thu, Sep 16 12:00 AM ET · T-Mobile Park, Seattle