MLB scores, schedule and odds: Tuesday, April 22, 2025

The MLB schedule for Tuesday, April 22, 2025 has 15 games.

• New York Yankees at Cleveland Guardians — NYY 2, CLE 3 (Final) · Progressive Field, Cleveland
• Cincinnati Reds at Miami Marlins — CIN 3, MIA 4 (Final) · loanDepot park, Miami
• San Diego Padres at Detroit Tigers — SD 2, DET 0 (Final) · Comerica Park, Detroit
• Baltimore Orioles at Washington Nationals — BAL 0, WSH 7 (Final) · Nationals Park, Washington
• Seattle Mariners at Boston Red Sox — SEA 3, BOS 8 (Final) · Fenway Park, Boston
• Philadelphia Phillies at New York Mets — PHI 1, NYM 5 (Final) · Citi Field, Queens
• St. Louis Cardinals at Atlanta Braves — STL 10, ATL 4 (Final) · Truist Park, Atlanta
• Chicago White Sox at Minnesota Twins — CHW 2, MIN 4 (Final) · Target Field, Minneapolis
• Colorado Rockies at Kansas City Royals — COL 3, KC 4 (Final/11) · Kauffman Stadium, Kansas City
• Los Angeles Dodgers at Chicago Cubs — LAD 10, CHC 11 (Final/10) · Wrigley Field, Chicago
• Toronto Blue Jays at Houston Astros — TOR 1, HOU 5 (Final) · Daikin Park, Houston
• Pittsburgh Pirates at Los Angeles Angels — PIT 9, LAA 3 (Final) · Angel Stadium, Anaheim
• Tampa Bay Rays at Arizona Diamondbacks — TB 1, ARI 5 (Final) · Chase Field, Phoenix
• Milwaukee Brewers at San Francisco Giants — MIL 11, SF 3 (Final) · Oracle Park, San Francisco
• Texas Rangers at Athletics — TEX 8, ATH 5 (Final) · Sutter Health Park, Sacramento