MLB scores, schedule and odds: Tuesday, September 22, 2026

The MLB schedule for Tuesday, September 22, 2026 has 16 games.

• Tampa Bay Rays at New York Yankees — TB 0, NYY 2 (Final) · Yankee Stadium, Bronx
• Toronto Blue Jays at Baltimore Orioles — TOR 0, BAL 0 (Postponed) · Oriole Park at Camden Yards, Baltimore
• Milwaukee Brewers at Philadelphia Phillies — MIL 4, PHI 6 (Final) · Citizens Bank Park, Philadelphia
• St. Louis Cardinals at Pittsburgh Pirates — STL 0, PIT 2 (Final) · PNC Park, Pittsburgh
• Washington Nationals at Detroit Tigers — WSH 3, DET 1 (Final) · Comerica Park, Detroit
• Cleveland Guardians at Boston Red Sox — CLE 3, BOS 2 (Final) · Fenway Park, Boston
• Tampa Bay Rays at New York Yankees — TB 6, NYY 1 (Final) · Yankee Stadium, Bronx
• Cincinnati Reds at Atlanta Braves — CIN 4, ATL 0 (Final) · Truist Park, Atlanta
• Chicago White Sox at Kansas City Royals — CHW 14, KC 11 (Final) · Kauffman Stadium, Kansas City
• Miami Marlins at Chicago Cubs — MIA 8, CHC 2 (Final/12) · Wrigley Field, Chicago
• New York Mets at Texas Rangers — NYM 6, TEX 3 (Final) · Globe Life Field, Arlington
• Arizona Diamondbacks at Colorado Rockies — ARI 7, COL 2 (Final) · Coors Field, Denver
• Los Angeles Angels at Athletics — LAA 7, ATH 9 (Final) · Sutter Health Park, Sacramento
• Houston Astros at Seattle Mariners — HOU 7, SEA 0 (Final) · T-Mobile Park, Seattle
• Minnesota Twins at San Francisco Giants — MIN 3, SF 2 (Final) · Oracle Park, San Francisco
• San Diego Padres at Los Angeles Dodgers — SD 0, LAD 7 (Final) · Dodger Stadium, Los Angeles