MLB scores, schedule and odds: Wednesday, September 16, 2026

The MLB schedule for Wednesday, September 16, 2026 has 15 games.

• Chicago White Sox at Cleveland Guardians — CHW 3, CLE 6 (Final) · Progressive Field, Cleveland
• San Francisco Giants at St. Louis Cardinals — SF 6, STL 5 (Final/10) · Busch Stadium, St. Louis
• New York Yankees at Minnesota Twins — NYY 4, MIN 5 (Final/13) · Target Field, Minneapolis
• Detroit Tigers at Toronto Blue Jays — DET 1, TOR 5 (Final) · Rogers Centre, Toronto
• Athletics at Tampa Bay Rays — ATH 3, TB 4 (Final) · Tropicana Field, St. Petersburg
• Los Angeles Dodgers at Cincinnati Reds — LAD 2, CIN 6 (Final) · Great American Ball Park, Cincinnati
• Milwaukee Brewers at Pittsburgh Pirates — MIL 5, PIT 4 (Final) · PNC Park, Pittsburgh
• Philadelphia Phillies at Washington Nationals — PHI 3, WSH 0 (Final) · Nationals Park, Washington
• Baltimore Orioles at New York Mets — BAL 7, NYM 1 (Final) · Citi Field, Queens
• Atlanta Braves at Chicago Cubs — ATL 4, CHC 8 (Final) · Wrigley Field, Chicago
• Boston Red Sox at Texas Rangers — BOS 3, TEX 7 (Final) · Globe Life Field, Arlington
• Kansas City Royals at Houston Astros — KC 5, HOU 2 (Final) · Daikin Park, Houston
• San Diego Padres at Colorado Rockies — SD 9, COL 3 (Final) · Coors Field, Denver
• Seattle Mariners at Los Angeles Angels — SEA 7, LAA 2 (Final) · Angel Stadium, Anaheim
• Miami Marlins at Arizona Diamondbacks — MIA 4, ARI 3 (Final) · Chase Field, Phoenix