MLB scores, schedule and odds: Wednesday, July 22, 2026

The MLB schedule for Wednesday, July 22, 2026 has 17 games.

• Pittsburgh Pirates at New York Yankees — PIT 5, NYY 3 (Final/10) · Yankee Stadium, Bronx
• Baltimore Orioles at Boston Red Sox — BAL 3, BOS 6 (Final) · Fenway Park, Boston
• New York Mets at Milwaukee Brewers — NYM 3, MIL 4 (Final) · American Family Field, Milwaukee
• San Francisco Giants at Kansas City Royals — SF 4, KC 5 (Final) · Kauffman Stadium, Kansas City
• Washington Nationals at Colorado Rockies — WSH 8, COL 0 (Final) · Coors Field, Denver
• Athletics at Arizona Diamondbacks — ATH 5, ARI 15 (Final) · Chase Field, Phoenix
• Cincinnati Reds at Seattle Mariners — CIN 5, SEA 3 (Final) · T-Mobile Park, Seattle
• St. Louis Cardinals at Los Angeles Angels — STL 1, LAA 0 (Final) · Angel Stadium, Anaheim
• Los Angeles Dodgers at Philadelphia Phillies — LAD 9, PHI 5 (Final) · Citizens Bank Park, Philadelphia
• Minnesota Twins at Cleveland Guardians — MIN 10, CLE 6 (Final) · Progressive Field, Cleveland
• Pittsburgh Pirates at New York Yankees — PIT 0, NYY 2 (Final) · Yankee Stadium, Bronx
• Tampa Bay Rays at Toronto Blue Jays — TB 4, TOR 2 (Final) · Rogers Centre, Toronto
• Baltimore Orioles at Boston Red Sox — BAL 5, BOS 1 (Final) · Fenway Park, Boston
• San Diego Padres at Atlanta Braves — SD 6, ATL 7 (Final) · Truist Park, Atlanta
• Detroit Tigers at Chicago Cubs — DET 5, CHC 1 (Final) · Wrigley Field, Chicago
• Chicago White Sox at Texas Rangers — CHW 4, TEX 2 (Final) · Globe Life Field, Arlington
• Miami Marlins at Houston Astros — MIA 2, HOU 5 (Final) · Daikin Park, Houston