MLB scores, schedule and odds: Sunday, September 21, 2025

The MLB schedule for Sunday, September 21, 2025 has 15 games.

• Atlanta Braves at Detroit Tigers — ATL 6, DET 2 (Final) · Comerica Park, Detroit
• New York Yankees at Baltimore Orioles — NYY 7, BAL 1 (Final/10) · Oriole Park at Camden Yards, Baltimore
• Athletics at Pittsburgh Pirates — ATH 0, PIT 11 (Final) · PNC Park, Pittsburgh
• Chicago Cubs at Cincinnati Reds — CHC 0, CIN 1 (Final) · Great American Ball Park, Cincinnati
• Washington Nationals at New York Mets — WSH 3, NYM 2 (Final) · Citi Field, Queens
• Cleveland Guardians at Minnesota Twins — CLE 2, MIN 6 (Final) · Target Field, Minneapolis
• San Diego Padres at Chicago White Sox — SD 3, CHW 2 (Final) · Rate Field, Chicago
• Toronto Blue Jays at Kansas City Royals — TOR 8, KC 5 (Final) · Kauffman Stadium, Kansas City
• Milwaukee Brewers at St. Louis Cardinals — MIL 1, STL 5 (Final) · Busch Stadium, St. Louis
• Miami Marlins at Texas Rangers — MIA 4, TEX 2 (Final) · Globe Life Field, Arlington
• Los Angeles Angels at Colorado Rockies — LAA 1, COL 3 (Final) · Coors Field, Denver
• Philadelphia Phillies at Arizona Diamondbacks — PHI 2, ARI 9 (Final) · Chase Field, Phoenix
• San Francisco Giants at Los Angeles Dodgers — SF 3, LAD 1 (Final) · Dodger Stadium, Los Angeles
• Seattle Mariners at Houston Astros — SEA 7, HOU 3 (Final) · Daikin Park, Houston
• Boston Red Sox at Tampa Bay Rays — BOS 3, TB 7 (Final) · George M. Steinbrenner Field, Tampa