La Liga scores, schedule and odds: Wednesday, April 21, 2027

The La Liga schedule for Wednesday, April 21, 2027 has 10 games.

First up: Atlético at Villarreal at 2:00 PM ET on ESPN+.

• Atlético Madrid at Villarreal — Wed, Apr 21 2:00 PM ET · Estadio de la Cerámica, Villarreal
• Rayo Vallecano at Valencia — Wed, Apr 21 2:00 PM ET · Mestalla Stadium, Manises
• Levante at Sevilla — Wed, Apr 21 2:00 PM ET · Ramón Sánchez Pizjuán Stadium, Sevilla
• Elche at Real Madrid — Wed, Apr 21 2:00 PM ET · Santiago Bernabéu, Madrid
• Málaga at Racing Santander — Wed, Apr 21 2:00 PM ET · El Sardineros, Santander
• Alavés at Osasuna — Wed, Apr 21 2:00 PM ET · El Sadar, Pamplona
• Real Betis at Getafe — Wed, Apr 21 2:00 PM ET · Estadio Coliseum, Getafe
• Real Sociedad at Espanyol — Wed, Apr 21 2:00 PM ET · RCDE Stadium, Barcelona
• Barcelona at Celta Vigo — Wed, Apr 21 2:00 PM ET · Balaidos, Vigo
• Deportivo at Athletic Club — Wed, Apr 21 2:00 PM ET · San Mamés, Bilbao